Search on: PAGET DISEASE EXTRAMAMMARY 
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Descriptor English:   Paget Disease, Extramammary 
Descriptor Spanish:   Enfermedad de Paget Extramamaria 
Descriptor Portuguese:   Doença de Paget Extramamária 
Synonyms English:   Paget Disease Extramammary
Paget's Disease, Extramammary  
Tree Number:   C04.557.470.200.025.660
C04.557.470.615.660
Definition English:   A rare cutaneous neoplasm that occurs in the elderly. It develops more frequently in women and predominantly involves apocrine gland-bearing areas, especially the vulva, scrotum, and perianal areas. The lesions develop as erythematous scaly patches that progress to crusted, pruritic, erythematous plaques. The clinical differential diagnosis includes squamous cell carcinoma in situ and superficial fungal infection. It is generally thought to be an adenocarcinoma of the epidermis, from which it extends into the contiguous epithelium of hair follicles and eccrine sweat ducts. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1478) 
Indexing Annotation English:   neoplastic; /blood supply /chem /second /secret /ultrastruct permitted; coord IM with precoord organ/neopl term (IM)
History Note English:   2010(1963) 
Allowable Qualifiers English:  
BS blood supply BL blood
CF cerebrospinal fluid CI chemically induced
CH chemistry CL classification
CO complications CN congenital
DI diagnosis DH diet therapy
DT drug therapy EC economics
EM embryology EN enzymology
EP epidemiology EH ethnology
ET etiology GE genetics
HI history IM immunology
ME metabolism MI microbiology
MO mortality NU nursing
PS parasitology PA pathology
PP physiopathology PC prevention & control
PX psychology RA radiography
RI radionuclide imaging RT radiotherapy
RH rehabilitation SC secondary
SE secretion SU surgery
TH therapy US ultrasonography
UL ultrastructure UR urine
VE veterinary VI virology
Record Number:   31760 
Unique Identifier:   D010145 

Occurrence in VHL:
 

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